Ligand · TFI
TFI · 2-[5-methanesulfonylamino-2-(4-aminophenyl)-6-oxo-1,6-dihydro-1-pyrimidinyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide
TFI, 2-[5-methanesulfonylamino-2-(4-aminophenyl)-6-oxo-1,6-dihydro-1-pyrimidinyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide (C19 H22 F3 N5 O5 S, 489.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…
- Component
- TFI
- Formula
- C19 H22 F3 N5 O5 S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
TFI in 2 structures; the first of them:
- 1EAT · Nonpeptidic inhibitors of human leukocyte elastase. 5. design, synthesis, and X-ray… · TFI A1 · binds THR41, CYS42, HIS57, CYS58, ARG61, ASP97, VAL99, TRP172 and 11 more
- 1EAT · Nonpeptidic inhibitors of human leukocyte elastase. 5. design, synthesis, and X-ray… · TFI A1 · binds THR41, CYS42, HIS57, CYS58, ARG61, ASP97, VAL99, TRP172 and 11 more
Residues it binds most
CYS 2, SER 2, ARG 2, ASP 2, THR 2, VAL 2, GLN 2, GLY 2, HIS 2, PHE 2 (residue and the binding sites it lines).
Found with
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