Ligand · TFF
TFF · 5'-O-[(R)-{[(R)-[difluoro(phosphono)methyl](hydroxy)phosphoryl](difluoro)methyl}(hydroxy)phosphoryl]thymidine
TFF, 5'-O-[(R)-{[(R)-[difluoro(phosphono)methyl](hydroxy)phosphoryl](difluoro)methyl}(hydroxy)phosphoryl]thymidine (C12 H17 F4 N2 O12 P3, 550.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…
- Component
- TFF
- Formula
- C12 H17 F4 N2 O12 P3
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
TFF in 2 structures; the first of them:
- 3LK9 · DNA polymerase beta with a gapped DNA substrate and dTMP(CF2)P(CF2)P · TFF A338 · binds ARG149, GLY179, SER180, ARG183, SER188, GLY189, ASP190, ASP192 and 11 more
- 3LK9 · DNA polymerase beta with a gapped DNA substrate and DTMP(CF2)P(CF2)P · TFF A338 · binds ARG149, GLY179, SER180, ARG183, SER188, GLY189, ASP190, ASP192 and 11 more
Residues it binds most
ASP 2, GLY 2, SER 2, ARG 2, ASN 2, DA 2, DC 2, DG 2, PHE 2, THR 2 (residue and the binding sites it lines).
Found with
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