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Ligand · TF2

TF2 · (N-{4-[(ethylanilino)sulfonyl]-2-methylphenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide

TF2, (N-{4-[(ethylanilino)sulfonyl]-2-methylphenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide (C19 H21 F3 N2 O4 S, 430.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
TF2
Formula
C19 H21 F3 N2 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

TF2 in 2 structures; the first of them:

  • 2BU6 · crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and… · TF2 A1386 · binds LEU23, GLN27, PHE28, PHE31, THR40, SER41, PHE44, LEU45 and 4 more
  • 2BU6 · Crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and… · TF2 A1386 · binds LEU23, GLN27, PHE28, PHE31, THR40, SER41, PHE44, LEU45 and 4 more

Residues it binds most

LEU 2, PHE 2, GLN 2, HIS 2, ILE 2, SER 2, THR 2 (residue and the binding sites it lines).

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