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Ligand · TEX

TEX · (2S,5S)-9-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one

TEX, (2S,5S)-9-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one (C27 H39 N3 O2, 437.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
TEX
Formula
C27 H39 N3 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

TEX in 2 structures; the first of them:

  • 5GM2 · Crystal structure of methyltransferase TleD complexed with SAH and teleocidin A1 · TEX A302 · binds GLU153, LEU155, CYS156, HIS157, ARG160, LEU180, GLU181, SER182 and 15 more
  • 5GM2 · Crystal structure of methyltransferase tled complexed with sah and teleocidin A1 · TEX A302 · binds GLU153, LEU155, CYS156, HIS157, ARG160, LEU180, GLU181, SER182 and 15 more

Residues it binds most

LEU 36, TYR 36, PHE 36, CYS 36, GLU 36, HIS 36, THR 36, SER 36, MET 36, PRO 36 (residue and the binding sites it lines).

Found with

  • SAH · S-adenosyl-L-homocysteine

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