GL1X · GenesisL1 explorer

Ligand · TBK

TBK · ~{N}-[[4-[[(2~{S})-4-cyclohexyl-1-[[(3~{S})-1-methylsulfonylpiperidin-3-yl]amino]-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide

TBK, ~{N}-[[4-[[(2~{S})-4-cyclohexyl-1-[[(3~{S})-1-methylsulfonylpiperidin-3-yl]amino]-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide (C32 H42 N6 O5 S, 622.8 g/mol), in the MolNFT structures on…

Component
TBK
Formula
C32 H42 N6 O5 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

TBK in 4 structures; the first of them:

  • 7BCM · The DDR1 Kinase Domain Bound To SR302 · TBK A1001 · binds LEU616, VAL624, ALA653, LYS655, GLU672, ILE675, MET676, LEU679 and 17 more
  • 7BDO · MAPK14 bound with SR302 · TBK A401 · binds VAL30, TYR35, VAL38, ALA51, LYS53, ARG67, GLU71, LEU74 and 16 more
  • 7BCM · The DDR1 kinase domain bound to SR302 · TBK A1001 · binds VAL624, ALA653, LYS655, GLU672, MET676, LEU679, ILE684, ILE685 and 11 more
  • 7BDO · MAPK14 bound with SR302 · TBK A401 · binds VAL30, TYR35, VAL38, ALA51, LYS53, ARG67, GLU71, LEU74 and 13 more

Residues it binds most

LEU 6, ILE 6, MET 6, ALA 6, ASP 6, PHE 6, VAL 6, HIS 6, GLY 5, GLU 6 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.