Ligand · T77

T77 · 6-{4-[2-(dimethylamino)ethoxy]phenyl}-N-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

T77, 6-{4-[2-(dimethylamino)ethoxy]phenyl}-N-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (C26 H29 N5 O S2, 491.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component: T77
Formula: C26 H29 N5 O S2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

T77 in 2 structures; the first of them:

4EWH · Co-crystal structure of ACK1 with inhibitor · T77 B401 · binds LEU132, GLY133, ASP134, GLY135, VAL140, ALA156, LYS158, ILE190 and 14 more
4EWH · Co-crystal structure of ACK1 with inhibitor · T77 B401 · binds LEU132, GLY133, ASP134, GLY135, VAL140, ALA156, LYS158, ILE190 and 14 more

Residues it binds most

GLY 4, LEU 4, ALA 4, ASP 4, LYS 4, ARG 4, ASN 4, GLU 4, ILE 4, PRO 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.