Ligand · T6Q
T6Q · 2-[[3-(4-ethanoyl-1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile
T6Q, 2-[[3-(4-ethanoyl-1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile (C23 H26 N8 O S, 462.6 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every…
- Component
- T6Q
- Formula
- C23 H26 N8 O S
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
T6Q in 4 structures; the first of them:
- 4BCF · Structure of CDK9 in complex with cyclin T and a 2-amino-4-heteroaryl- pyrimidine… · T6Q A1327 · binds ILE25, PHE30, VAL33, ALA46, LYS48, VAL79, PHE103, ASP104 and 9 more
- 4BCO · Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine… · T6Q A1299 · binds GLU8, ILE10, GLU12, GLY13, THR14, VAL18, LYS20, ALA31 and 15 more
- 4BCF · Structure of CDK9 in complex with cyclin T and a 2-amino-4-heteroaryl- pyrimidine… · T6Q A1327 · binds ILE25, PHE30, VAL33, ALA46, LYS48, VAL79, PHE103, ASP104 and 9 more
- 4BCO · Structure of CDK2 in complex with cyclin a and a 2-amino-4- heteroaryl-pyrimidine… · T6Q A1299 · binds GLU8, ILE10, GLU12, GLY13, THR14, VAL18, LYS20, ALA31 and 15 more
Residues it binds most
ASP 6, LYS 6, PHE 6, ALA 6, GLU 6, VAL 6, LEU 6, GLN 4, ASN 6, HIS 6 (residue and the binding sites it lines).
Found with
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