GL1X · GenesisL1 explorer

Ligand · T2Z

T2Z · [(2~{S},3~{S},4~{E},6~{S},7~{R},10~{R})-3,7-dimethyl-2-[(2~{E},4~{E},6~{R})-6-methyl-6-oxidanyl-7-[(2~{R}, 3~{R})-3-[(2~{R},3~{S})-3-oxidanylpentan-2-yl]oxiran-2-yl]hepta-2,4-dien-2-yl]-7,10-bis(oxidanyl)-12-oxidanylidene-1-oxacyclododec-4-en-6-yl] ethanoate

T2Z, [(2~{S},3~{S},4~{E},6~{S},7~{R},10~{R})-3,7-dimethyl-2-[(2~{E},4~{E},6~{R})-6-methyl-6-oxidanyl-7-[(2~{R}, 3~{R})-3-[(2~{R},3~{S})-3-oxidanylpentan-2-yl]oxiran-2-yl]hepta-2,4-dien-2-yl]-7,10-bis(oxidanyl)-12-oxidanylidene-1-oxacyclodod…

Component
T2Z
Formula
C30 H48 O9
Class
ligand
Structures
1
PDB entries
1

Binding sites

T2Z in 1 structure; the first of them:

  • 7B91 · Structure of a minimal SF3B core in complex with pladienolide D (form I) · T2Z D1401 · binds LEU1066, LYS1067, LYS1071, ARG1074, VAL1078, PHE1153, TYR1157, ASP34 and 3 more

Residues it binds most

ARG 1, LYS 1, TYR 1, VAL 1, ASP 1, LEU 1, PHE 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.