GL1X · GenesisL1 explorer

Ligand · T22

T22 · 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile

T22, 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile (C18 H21 N5 O2, 339.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
T22
Formula
C18 H21 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

T22 in 2 structures; the first of them:

  • 3G0B · Crystal structure of dipeptidyl peptidase IV in complex with TAK-322 · T22 A805 · binds ARG125, GLU205, GLU206, PHE357, TYR547, TRP629, SER630, TYR631 and 7 more
  • 3G0B · Crystal structure of dipeptidyl peptidase IV in complex with tak-322 · T22 A800 · binds ARG125, GLU205, GLU206, PHE357, TYR547, TRP629, SER630, TYR631 and 7 more

Residues it binds most

TYR 8, GLU 8, TRP 8, VAL 8, ARG 8, ASN 8, HIS 8, PHE 8, SER 8 (residue and the binding sites it lines).

Found with

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.