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Ligand · T0P

T0P · [(2~{R},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-7-phenacyl-1~{H}-purin-9-yl)-4-fluoranyl-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate

T0P, [(2~{R},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-7-phenacyl-1~{H}-purin-9-yl)-4-fluoranyl-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate (C18 H20 F N5 O8 P, 484.4 g/mol), in the MolNFT structures on GenesisL1: bound in 1…

Component
T0P
Formula
C18 H20 F N5 O8 P
Class
ligand
Structures
1
PDB entries
1

Binding sites

T0P in 1 structure; the first of them:

  • 7LCD · Crystal structure of human polymerase eta complexed with syn N7- acetophenoneguanine · T0P T4 · binds PHE18, GLN38, TYR39, ILE48, ARG61, ASN324, PRO326, DT3 and 2 more

Residues it binds most

ARG 1, ASN 1, DC 1, DG 1, DT 1, GLN 1, ILE 1, PHE 1, PRO 1, TYR 1 (residue and the binding sites it lines).

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