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Ligand · SZ6

SZ6 · N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-N-(4-{[(difluoroacetyl)amino]methyl}benzyl)-2,4-dihydroxybenzamide

SZ6, N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-N-(4-{[(difluoroacetyl)amino]methyl}benzyl)-2,4-dihydroxybenzamide (C28 H23 Cl F2 N4 O4, 553.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
SZ6
Formula
C28 H23 Cl F2 N4 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

SZ6 in 2 structures; the first of them:

  • 4V25 · VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase… · SZ6 A1369 · binds LEU244, LYS246, ASN247, ALA248, ARG250, ALA251, GLU254, SER255 and 11 more
  • 4V25 · Ver-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase… · SZ6 A1369 · binds LEU244, LYS246, ASN247, ALA248, ARG250, ALA251, GLU254, SER255 and 11 more

Residues it binds most

ALA 2, LEU 2, GLY 2, SER 2, ARG 2, ASN 2, ASP 2, GLU 2, LYS 2, THR 2 (residue and the binding sites it lines).

Found with

  • TF3 · N-(2-aminoethyl)-2-{3-chloro-4-[(4-isopropylbenzyl) oxy]phenyl} acetamide
  • MG · Magnesium ion

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