GL1X · GenesisL1 explorer

Ligand · SXF

SXF · [(1~{S},3~{R},4~{S},5~{R},6~{R},8~{R},10~{S},23~{R},24~{R},25~{R},26~{R})-5-acetyloxy-6-methyl-4,26-bis(oxidanyl)-17,20-bis(oxidanylidene)-10-pentyl-24-[(~{E})-3-phenylprop-2-enoyl]oxy-2,7,9,21,27-pentaoxatricyclo[21.3.1.0^{3,8}]heptacosan-25-yl] (~{E})-2-methylbut-2-enoate

SXF, [(1~{S},3~{R},4~{S},5~{R},6~{R},8~{R},10~{S},23~{R},24~{R},25~{R},26~{R})-5-acetyloxy-6-methyl-4,26-bis(oxidanyl)-17,20-bis(oxidanylidene)-10-pentyl-24-[(~{E})-3-phenylprop-2-enoyl]oxy-2,7,9,21,27-pentaoxatricyclo[21.3.1.0^{3,8}]heptac…

Component
SXF
Formula
C44 H62 O15
Class
ligand
Structures
1
PDB entries
1

Binding sites

SXF in 1 structure; the first of them:

  • 8DO1 · Cryo-EM structure of the human Sec61 complex inhibited by ipomoeassin F · SXF A501 · binds PHE62, MET65, ILE68, LEU69, LEU79, ILE81, SER82, VAL85 and 18 more

Residues it binds most

ILE 1, LEU 1, GLN 1, GLY 1, VAL 1, ALA 1, ASN 1, MET 1, PHE 1, SER 1 (residue and the binding sites it lines).

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