GL1X · GenesisL1 explorer

Ligand · SVN

SVN · thieno[2,3-b]pyrazin-7-amine

SVN, thieno[2,3-b]pyrazin-7-amine (C6 H5 N3 S, 151.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
SVN
Formula
C6 H5 N3 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

SVN in 4 structures; the first of them:

  • 4CTK · Dengue 3 NS5 methyltransferase bound to S-adenosyl methionine and fragment 2A4 · SVN A1264 · binds LEU17, ASN18, LEU20, SER21, ARG22, PHE25
  • 4NYC · Crystal structure of the E. coli thiM riboswitch in complex with… · SVN A101 · binds G19, U20, G40, G42, A43, C73
  • 4CTK · Dengue 3 NS5 methyltransferase bound to S-adenosyl methionine and fragment 2A4 · SVN A1264 · binds LEU17, ASN18, LEU20, SER21, ARG22, PHE25
  • 4NYC · Crystal structure of the E. COLI thim riboswitch in complex with… · SVN A101 · binds G19, U20, G40, G42, A43, C73

Residues it binds most

G 2, ASN 4, LEU 2, A 2, ARG 2, C 2, PHE 2, PRO 2, SER 2, U 2 (residue and the binding sites it lines).

Found with

  • SAM · S-adenosylmethionine
  • MG · Magnesium ion
  • MN · Manganese (II) ion
  • NA · Sodium ion
  • DMS · Dimethyl sulfoxide

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