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Ligand · STD

STD · Streptolydigin

STD, Streptolydigin (C32 H44 N2 O9, 600.7 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
STD
Formula
C32 H44 N2 O9
Class
ligand
Structures
6
PDB entries
3

Binding sites

STD in 6 structures; the first of them:

  • 1ZYR · Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the… · STD D1525 · binds ARG422, ALA423, GLY424, PHE425, ARG428, GLY446, ALA447, ALA1082 and 5 more
  • 2A6H · Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with… · STD D8001 · binds GLU421, ARG422, ALA423, PHE425, ARG428, ALA447, ILE449, GLY1081 and 6 more
  • 2PPB · Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp… · STD D7001 · binds DC4, DG5, DC6, ARG422, PHE425, ARG428, ALA447, ILE449 and 8 more
  • 1ZYR · Structure of thermus thermophilus RNA polymerase holoenzyme in complex with the… · STD D1525 · binds ARG422, ALA423, GLY424, PHE425, ARG428, GLY446, ALA447, ALA1082 and 5 more
  • 2A6H · Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with… · STD D8001 · binds GLU421, ARG422, ALA423, PHE425, ARG428, ALA447, ILE449, GLY1081 and 6 more
  • 2PPB · Crystal structure of the T. thermophilus rnap polymerase elongation complex with the ntp… · STD D7001 · binds DC4, DG5, DC6, ARG422, PHE425, ARG428, ALA447, ILE449 and 8 more

Residues it binds most

ALA 12, ARG 12, ASP 12, ILE 10, LEU 12, PHE 12, PRO 12, GLY 8, DC 4, DG 4 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • APC · Diphosphomethylphosphonic acid adenosyl ester

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