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Ligand · SLO

SLO · 2-[(3Z)-6-fluoranyl-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]ethanoic acid

SLO, 2-[(3Z)-6-fluoranyl-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]ethanoic acid (C20 H17 F O4 S, 372.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
SLO
Formula
C20 H17 F O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

SLO in 2 structures; the first of them:

  • 3RX2 · Crystal Structure of Human Aldose Reductase Complexed with Sulindac Sulfone · SLO A317 · binds TRP20, VAL47, TYR48, TRP79, HIS110, TRP111, PHE122, LEU124 and 4 more
  • 3RX2 · Crystal structure of human aldose reductase complexed with sulindac sulfone · SLO A317 · binds TRP20, VAL47, TYR48, TRP79, HIS110, TRP111, PHE122, LEU124 and 4 more

Residues it binds most

TRP 2, LEU 2, CYS 2, HIS 2, PHE 2, SER 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

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