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Ligand · SL7

SL7 · 5-[[3-[3-(dimethylamino)-1,2,4-oxadiazol-5-yl]-2-oxidanyl-phenyl]methylamino]-2~{H}-indazole-3-carboxylic acid

SL7, 5-[[3-[3-(dimethylamino)-1,2,4-oxadiazol-5-yl]-2-oxidanyl-phenyl]methylamino]-2~{H}-indazole-3-carboxylic acid (C19 H18 N6 O4, 394.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
SL7
Formula
C19 H18 N6 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

SL7 in 2 structures; the first of them:

  • 6W4C · Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 5 · SL7 A402 · binds SER22, ILE23, TYR26, ALA81, MET82, MET85, TRP110, TYR132 and 11 more
  • 6W4C · Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 5 · SL7 A402 · binds SER22, TYR26, ALA81, MET82, MET85, TRP110, TYR132, ARG167 and 8 more

Residues it binds most

ARG 2, ALA 2, MET 2, TYR 2, ASP 2, GLY 2, HIS 2, LEU 1, PHE 2, SER 2 (residue and the binding sites it lines).

Found with

  • FMN · Flavin mononucleotide

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