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Ligand · SKP

SKP · 5-(1-carboxy-1-phosphonooxy-ethoxyl)-4-hydroxy-3-phosphonooxy-cyclohex-1-enecarboxylic acid

SKP, 5-(1-carboxy-1-phosphonooxy-ethoxyl)-4-hydroxy-3-phosphonooxy-cyclohex-1-enecarboxylic acid (C10 H16 O14 P2, 422.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues…

Component
SKP
Formula
C10 H16 O14 P2
Class
ligand
Structures
4
PDB entries
2

Binding sites

SKP in 4 structures; the first of them:

  • 1Q36 · EPSP synthase (Asp313Ala) liganded with tetrahedral reaction intermediate · SKP A600 · binds LYS22, SER23, ARG27, ASP49, ASN94, ALA95, GLY96, THR97 and 18 more
  • 2O0X · Mycobacterium tuberculosis epsp synthase in complex with intermediate · SKP A501 · binds LYS23, SER24, ARG28, ASP54, LEU94, ALA95, GLY96, THR97 and 18 more
  • 1Q36 · Epsp synthase (ASP313ALA) liganded with tetrahedral reaction intermediate · SKP A600 · binds LYS22, SER23, ARG27, ASP49, ASN94, ALA95, GLY96, THR97 and 18 more
  • 2O0X · Mycobacterium tuberculosis epsp synthase in complex with intermediate · SKP A501 · binds LYS23, SER24, ARG28, ASP54, LEU94, ALA95, GLY96, THR97 and 18 more

Residues it binds most

ARG 4, SER 4, HIS 4, LYS 4, ALA 4, GLU 4, THR 4, ASN 2, ASP 4, GLN 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • FMT · Formic acid

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