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Ligand · SKK

SKK · N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide

SKK, N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide (C19 H25 N7 O2, 383.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
SKK
Formula
C19 H25 N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

SKK in 2 structures; the first of them:

  • 3WQH · Crystal Structure of human DPP-IV in complex with Anagliptin · SKK A808 · binds ARG125, GLU205, GLU206, SER209, PHE357, TYR547, TYR585, SER630 and 8 more
  • 3WQH · Crystal structure of human dpp-IV in complex with anagliptin · SKK A808 · binds ARG125, GLU205, GLU206, SER209, PHE357, TYR547, TYR585, SER630 and 8 more

Residues it binds most

TYR 4, GLU 4, SER 4, VAL 4, ARG 4, ASN 4, HIS 4, PHE 4, TRP 4 (residue and the binding sites it lines).

Found with

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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