GL1X · GenesisL1 explorer

Ligand · SKA

SKA · 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline

SKA, 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline (C9 H9 Cl2 N, 202.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
SKA
Formula
C9 H9 Cl2 N
Class
ligand
Structures
2
PDB entries
1

Binding sites

SKA in 2 structures; the first of them:

  • 1YZ3 · Structure of human pnmt complexed with cofactor product adohcy and inhibitor SK&F 64139 · SKA A3001 · binds TYR35, ASN39, TYR40, ARG44, VAL53, LYS57, PHE182, ALA216 and 6 more
  • 1YZ3 · Structure of human pnmt complexed with cofactor product adohcy and inhibitor SK&F 64139 · SKA A3001 · binds TYR35, ASN39, TYR40, ARG44, VAL53, LYS57, PHE182, ALA216 and 6 more

Residues it binds most

TYR 4, VAL 4, ALA 4, ARG 4, ASN 4, ASP 4, GLU 4, LYS 4, MET 4, PHE 4 (residue and the binding sites it lines).

Found with

  • SAH · S-adenosyl-L-homocysteine

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.