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Ligand · SK4

SK4 · 4-[(3-methoxyphenyl)amino]-6-(methylsulfonyl)quinoline-3-carboxamide

SK4, 4-[(3-methoxyphenyl)amino]-6-(methylsulfonyl)quinoline-3-carboxamide (C18 H17 N3 O4 S, 371.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
SK4
Formula
C18 H17 N3 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

SK4 in 2 structures; the first of them:

  • 3FRG · Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with a Quinoline Inhibitor · SK4 A1 · binds TYR233, HIS234, THR345, MET347, ASP392, LEU393, ASN395, ILE410 and 5 more
  • 3FRG · Catalytic domain of human phosphodiesterase 4B2B in complex with a quinoline inhibitor · SK4 A1 · binds TYR233, HIS234, THR345, MET347, ASP392, LEU393, ASN395, ILE410 and 5 more

Residues it binds most

MET 2, PHE 2, ASN 2, ASP 2, GLN 2, HIS 2, ILE 2, LEU 2, THR 2, TYR 2 (residue and the binding sites it lines).

Found with

  • ARS · Arsenic
  • MG · Magnesium ion
  • ZN · Zinc ion
  • GOL · Glycerol

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