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Ligand · SK2

SK2 · (3R)-methylcarbamoyl-7-sulfoamino-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester

SK2, (3R)-methylcarbamoyl-7-sulfoamino-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester (C19 H21 N3 O6 S, 419.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
SK2
Formula
C19 H21 N3 O6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

SK2 in 2 structures; the first of them:

  • 2F6V · Protein tyrosine phosphatase 1B with sulfamic acid inhibitors · SK2 A608 · binds ARG24, TYR46, ASP48, VAL49, LYS120, ASP181, PHE182, CYS215 and 9 more
  • 2F6V · Protein tyrosine phosphatase 1B with sulfamic acid inhibitors · SK2 A608 · binds ARG24, TYR46, ASP48, VAL49, LYS120, ASP181, PHE182, CYS215 and 9 more

Residues it binds most

GLY 2, ARG 2, ASP 2, ALA 2, CYS 2, GLN 2, ILE 2, LYS 2, MET 2, PHE 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • CL · Chloride ion

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