Ligand · SG8
SG8 · 3-chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[3-(pyridin-4-yl)benzyl]-1-benzothiophene-2-carboxamide
SG8, 3-chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[3-(pyridin-4-yl)benzyl]-1-benzothiophene-2-carboxamide (C28 H26 Cl F2 N3 O S, 526.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- SG8
- Formula
- C28 H26 Cl F2 N3 O S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
SG8 in 2 structures; the first of them:
- 4QIN · Structure of the human smoothened receptor in complex with SAG1.5 · SG8 A1201 · binds ILE215, ASN219, PRO220, LEU221, PHE222, MET301, LEU303, GLY383 and 13 more
- 4QIN · Structure of the human smoothened receptor in complex with SAG1.5 · SG8 A1201 · binds ILE215, ASN219, PRO220, LEU221, PHE222, MET301, LEU303, GLY383 and 13 more
Residues it binds most
ASP 2, GLU 2, LEU 2, PHE 2, PRO 2, ARG 2, ASN 2, GLN 2, GLY 2, HIS 2 (residue and the binding sites it lines).
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