Ligand · SFM
SFM · (13E,15E)-(3S,6S,9R,10R,11S,12S,18S,21S)-10,12-dihydroxy-3-(3-hydroxyben-zyl)-18-((E)-3-hydroxy-1-methylpropenyl)-6-isopropyl-11-methyl-9-(3-oxo-butyl)-19-oxa-1,4,7,25-tetraaza-bicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetraone
SFM, (13E,15E)-(3S,6S,9R,10R,11S,12S,18S,21S)-10,12-dihydroxy-3-(3-hydroxyben-zyl)-18-((E)-3-hydroxy-1-methylpropenyl)-6-isopropyl-11-methyl-9-(3-oxo-butyl)-19-oxa-1,4,7,25-tetraaza-bicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetraone…
- Component
- SFM
- Formula
- C39 H56 N4 O10
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
SFM in 2 structures; the first of them:
- 1NMK · The Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic… · SFM A166 · binds ARG55, ILE57, PHE60, MET61, GLN63, ARG69, GLY72, THR73 and 10 more
- 1NMK · The sanglifehrin-cyclophilin interaction: degradation work, synthetic macrocyclic… · SFM A166 · binds ARG55, ILE57, PHE60, MET61, GLN63, ARG69, GLY72, THR73 and 10 more
Residues it binds most
ALA 4, GLN 4, PHE 4, TRP 4, ARG 4, LYS 4, ASN 4, GLY 4, HIS 4, ILE 4 (residue and the binding sites it lines).
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