Ligand · SFI
SFI · 2-[(3Z)-6-fluoranyl-2-methyl-3-[(4-methylsulfanylphenyl)methylidene]inden-1-yl]ethanoic acid
SFI, 2-[(3Z)-6-fluoranyl-2-methyl-3-[(4-methylsulfanylphenyl)methylidene]inden-1-yl]ethanoic acid (C20 H17 F O2 S, 340.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…
- Component
- SFI
- Formula
- C20 H17 F O2 S
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
SFI in 4 structures; the first of them:
- 3RX4 · Crystal Structure of Human Aldose Reductase complexed with Sulindac Sulfide · SFI A317 · binds TRP20, VAL47, TYR48, HIS110, TRP111, PHE122, TRP219, CYS298 and 2 more
- 4XUH · PPARgamma ligand binding domain in complex with sulindac sulfide · SFI A501 · binds LEU255, GLU259, PHE264, ARG280, ILE281, GLY284, CYS285, ARG288 and 8 more
- 3RX4 · Crystal structure of human aldose reductase complexed with sulindac sulfide · SFI A317 · binds TRP20, VAL47, TYR48, HIS110, TRP111, PHE122, TRP219, CYS298 and 2 more
- 4XUH · Ppargamma ligand binding domain in complex with sulindac sulfide · SFI A501 · binds LEU255, GLU259, PHE264, ARG280, ILE281, GLY284, CYS285, ARG288 and 8 more
Residues it binds most
LEU 10, PHE 10, ILE 8, MET 8, HIS 8, CYS 10, SER 10, TYR 6, VAL 8, ARG 4 (residue and the binding sites it lines).
Found with
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
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