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Ligand · SA3

SA3 · 2,10-dihydroxy-12-(beta-D-glucopyranosyl)-6,7,12,13-tetrahydroindolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione

SA3, 2,10-dihydroxy-12-(beta-D-glucopyranosyl)-6,7,12,13-tetrahydroindolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione (C26 H21 N3 O9, 519.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
SA3
Formula
C26 H21 N3 O9
Class
ligand
Structures
2
PDB entries
1

Binding sites

SA3 in 2 structures; the first of them:

  • 1SEU · Human DNA Topoisomerase I (70 Kda) In Complex With The Indolocarbazole SA315F and… · SA3 D990 · binds DT9, DT10, TGP11, DC112, DA113, ALA351, ASN352, GLU356 and 4 more
  • 1SEU · Human DNA topoisomerase I (70 kda) in complex with the indolocarbazole SA315F and… · SA3 D990 · binds DT9, DT10, TGP11, DC112, DA113, ALA351, ASN352, GLU356 and 4 more

Residues it binds most

DT 2, ALA 2, ARG 2, ASN 2, DA 2, DC 2, GLU 2, MET 2, SER 2, TGP 2 (residue and the binding sites it lines).

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