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Ligand · S6L

S6L · 2-amino-N-[4-(2-amino-1-benzyl-3-cyano-indol-5-yl)oxyphenyl]acetamide

S6L, 2-amino-N-[4-(2-amino-1-benzyl-3-cyano-indol-5-yl)oxyphenyl]acetamide (C24 H21 N5 O2, 411.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
S6L
Formula
C24 H21 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

S6L in 2 structures; the first of them:

  • 5AJW · Human PFKFB3 in complex with an indole inhibitor 2 · S6L A1449 · binds ALA44, ARG45, GLY46, TYR49, ILE50, SER152, CYS154, VAL159 and 11 more
  • 5AJW · Human PFKFB3 in complex with an indole inhibitor 2 · S6L A1449 · binds ALA44, ARG45, GLY46, TYR49, ILE50, SER152, CYS154, VAL159 and 11 more

Residues it binds most

VAL 2, ASN 2, GLY 2, ILE 2, ALA 2, ARG 2, CYS 2, HIS 2, LEU 2, MET 2 (residue and the binding sites it lines).

Found with

  • F6P · 6-O-phosphono-beta-D-fructofuranose
  • PHS · Phosphonic acid
  • PO4 · Phosphate ion

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