Ligand · S4K

S4K · 1-(4-fluorophenyl)-N-[3-fluoro-4-[(3-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,3-dimethyl-5-oxopyrazole-4-carboxamide

S4K, 1-(4-fluorophenyl)-N-[3-fluoro-4-[(3-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,3-dimethyl-5-oxopyrazole-4-carboxamide (C31 H23 F2 N5 O3, 551.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component: S4K
Formula: C31 H23 F2 N5 O3
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

S4K in 2 structures; the first of them:

7AVX · MerTK kinase domain in complex with NPS-1034 · S4K A901 · binds LEU593, GLY594, VAL601, ALA617, LYS619, MET621, PHE634, GLU637 and 15 more
7AVX · Mertk kinase domain in complex with nps-1034 · S4K A901 · binds LEU593, GLY594, VAL601, ALA617, LYS619, MET621, PHE634, GLU637 and 13 more

Residues it binds most

LEU 4, MET 4, PHE 4, ALA 4, VAL 4, GLY 4, ASP 4, ILE 4, LYS 4, PRO 4 (residue and the binding sites it lines).

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