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Ligand · S3Z

S3Z · ~{N}-[(1~{R})-1-[3-azanyl-5-(trifluoromethyl) phenyl]ethyl]-6,7-dimethoxy-2-methyl-quinazolin-4-amine

S3Z, ~{N}-[(1~{R})-1-[3-azanyl-5-(trifluoromethyl) phenyl]ethyl]-6,7-dimethoxy-2-methyl-quinazolin-4-amine (C20 H21 F3 N4 O2, 406.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
S3Z
Formula
C20 H21 F3 N4 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

S3Z in 2 structures; the first of them:

  • 7AVU · Crystal structure of SOS1 in complex with compound 8 · S3Z A1102 · binds VAL875, MET878, ASN879, VAL883, TYR884, PHE890, LYS898, LEU901 and 2 more
  • 7AVU · Crystal structure of SOS1 in complex with compound 8 · S3Z A1102 · binds VAL875, MET878, ASN879, VAL883, TYR884, PHE890, LYS898, LEU901 and 2 more

Residues it binds most

GLU 4, VAL 4, ASN 4, HIS 4, LEU 4, LYS 4, MET 4, PHE 4, TYR 4, ARG 2 (residue and the binding sites it lines).

Found with

  • IMD · Imidazole

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