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Ligand · S2P

S2P · (2S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid

S2P, (2S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid (C5 H7 N3 O3 S, 189.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
S2P
Formula
C5 H7 N3 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

S2P in 2 structures; the first of them:

  • 3BFT · Structure of the ligand-binding core of GluR2 in complex with the agonist (S)-TDPA at… · S2P A1009 · binds TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141, SER142 and 6 more
  • 3BFT · Structure of the ligand-binding core of GLUR2 in complex with the agonist (S)-tdpa at… · S2P A1009 · binds TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141, SER142 and 6 more

Residues it binds most

LEU 6, THR 6, TYR 6, ARG 6, GLU 6, GLY 6, MET 6, PRO 6, SER 6 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • ZN · Zinc ion
  • CL · Chloride ion
  • CAC · Cacodylate ion

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