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Ligand · S19

S19 · 2-{[(3R,4R)-3-aminotetrahydro-2H-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide

S19, 2-{[(3R,4R)-3-aminotetrahydro-2H-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide (C17 H22 N6 O2, 342.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
S19
Formula
C17 H22 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

S19 in 2 structures; the first of them:

  • 3SRV · Crystal structure of spleen tyrosine kinase (SYK) in complex with a diaminopyrimidine… · S19 A1 · binds LEU377, GLY378, PHE382, VAL385, ALA400, LYS402, VAL433, MET448 and 10 more
  • 3SRV · Crystal structure of spleen tyrosine kinase (syk) in complex with a diaminopyrimidine… · S19 A1 · binds LEU377, GLY378, PHE382, VAL385, ALA400, LYS402, VAL433, MET448 and 10 more

Residues it binds most

ALA 4, GLY 4, LEU 4, MET 4, VAL 4, SER 4, ARG 4, ASN 4, ASP 4, GLU 4 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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