Ligand · RW4
RW4 · 3-(2-amino-1,3-benzothiazol-6-yl)-1-{[2-(4-methylpiperazin-1-yl)quinolin-3-yl]methyl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine
RW4, 3-(2-amino-1,3-benzothiazol-6-yl)-1-{[2-(4-methylpiperazin-1-yl)quinolin-3-yl]methyl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine (C27 H26 N10 S, 522.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- RW4
- Formula
- C27 H26 N10 S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
RW4 in 2 structures; the first of them:
- 2WXK · The crystal structure of the murine class IA PI 3-kinase p110delta in complex with INK666. · RW4 A1500 · binds THR750, PHE751, MET752, PRO758, LEU759, TRP760, ILE777, LYS779 and 13 more
- 2WXK · The crystal structure of the murine class ia pi 3-kinase P110DELTA in complex with INK666. · RW4 A1500 · binds THR750, PHE751, MET752, PRO758, LEU759, TRP760, ILE777, LYS779 and 13 more
Residues it binds most
ASP 2, ILE 2, LEU 2, MET 2, VAL 2, ASN 2, GLU 2, LYS 2, PHE 2, PRO 2 (residue and the binding sites it lines).
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