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Ligand · RTO

RTO · 4-(dipropylsulfamoyl)benzoic acid

RTO, 4-(dipropylsulfamoyl)benzoic acid (C13 H19 N O4 S, 285.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
RTO
Formula
C13 H19 N O4 S
Class
ligand
Structures
3
PDB entries
3

Binding sites

RTO in 3 structures; the first of them:

  • 8BVT · Cryo-EM structure of rat SLC22A6 bound to probenecid · RTO A601 · binds MET31, ASN35, ALA203, ILE204, MET207, ILE226, TYR230, TYR354 and 3 more
  • 8RQ4 · Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in complex… · RTO A1701 · binds TYR377, PHE378, CYS381, PHE382, ASN432, TYR433, LEU436, PHE587 and 5 more
  • 8SDZ · Structure of rat organic anion transporter 1 (OAT1) in complex with probenecid · RTO A601 · binds ASN35, MET142, VAL145, TYR230, TRP346, SER350, TYR353, TYR354 and 9 more

Residues it binds most

PHE 4, TYR 3, ASN 3, ARG 3, MET 3, SER 2, ALA 2, TRP 3, ASP 2, GLN 1 (residue and the binding sites it lines).

Found with

  • Y01 · Cholesterol hemisuccinate

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