GL1X · GenesisL1 explorer

Ligand · RSY

RSY · N-[(2R)-1-{[(2S,3S)-5-{[(2R)-1-{[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino}-3-chloro-1-oxopropan-2-yl]amino}-3-hydroxy-5-oxo-1-phenylpentan-2-yl]amino}-3-methyl-1-oxobutan-2-yl]pyridine-2-carboxamide

RSY, N-[(2R)-1-{[(2S,3S)-5-{[(2R)-1-{[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino}-3-chloro-1-oxopropan-2-yl]amino}-3-hydroxy-5-oxo-1-phenylpentan-2-yl]amino}-3-methyl-1-oxobutan-2-yl]pyridine-2-carboxamide (C31 H43 Cl N6 O6, 631.2…

Component
RSY
Formula
C31 H43 Cl N6 O6
Class
ligand
Structures
2
PDB entries
1

Binding sites

RSY in 2 structures; the first of them:

  • 3R0W · Crystal Structures of Multidrug-resistant HIV-1 Protease in Complex with Mechanism-Based… · RSY A301 · binds LEU23, ASN25, GLY27, ALA28, ASP29, ASP30, VAL32, THR80 and 12 more
  • 3R0W · Crystal structures of multidrug-resistant HIV-1 protease in complex with mechanism-based… · RSY A301 · binds LEU23, ASN25, GLY27, ALA28, ASP29, ASP30, VAL32, THR80 and 12 more

Residues it binds most

GLY 2, THR 2, VAL 2, ALA 2, ASN 2, ASP 2, ILE 2, LEU 2, PRO 2 (residue and the binding sites it lines).

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