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Ligand · RQT

RQT · ~{N}-[3-(1~{H}-pyrrolo[2,3-b]pyridin-3-yl) phenyl]propanamide

RQT, ~{N}-[3-(1~{H}-pyrrolo[2,3-b]pyridin-3-yl) phenyl]propanamide (C16 H15 N3 O, 265.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
RQT
Formula
C16 H15 N3 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

RQT in 2 structures; the first of them:

  • 7APG · Crystal structure of JAK3 in complex with FM587 (compound 9a) · RQT A1201 · binds LEU828, GLY829, VAL836, ALA853, VAL884, MET902, GLU903, TYR904 and 7 more
  • 7APG · Crystal structure of JAK3 in complex with FM587 (compound 9A) · RQT A1201 · binds LEU828, GLY829, VAL836, ALA853, GLU903, TYR904, LEU905, CYS909 and 4 more

Residues it binds most

LEU 8, ARG 8, GLY 8, VAL 7, ALA 8, ASP 8, CYS 8, GLU 8, TYR 8, MET 4 (residue and the binding sites it lines).

Found with

  • PHU · 1-phenylurea
  • EDO · 1,2-ethanediol

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