Ligand · ROQ
ROQ · (3~{S})-3-methyl-2-oxidanylidene-pentanedioic acid
ROQ, (3~{S})-3-methyl-2-oxidanylidene-pentanedioic acid (C6 H8 O5, 160.1 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…
- Component
- ROQ
- Formula
- C6 H8 O5
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
ROQ in 6 structures; the first of them:
- 7A1L · FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II) AND 3-methyl-2-oxoglutarate · ROQ A401 · binds TYR145, LEU186, LEU188, THR196, HIS199, ASP201, ASN205, PHE207 and 5 more
- 7A1N · FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 3-methyl-2-oxoglutarate, AND… · ROQ A1008 · binds TYR145, LEU188, THR196, HIS199, ASP201, ASN205, PHE207, LYS214 and 5 more
- 7A1S · FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 3-methyl-2-oxoglutarate, AND… · ROQ A609 · binds TYR145, LEU186, LEU188, THR196, HIS199, ASP201, ASN205, PHE207 and 5 more
- 7A1L · Factor inhibiting hif-1 alpha in complex with ZN(II) and 3-methyl-2- oxoglutarate · ROQ A401 · binds TYR145, LEU186, LEU188, THR196, HIS199, ASP201, ASN205, PHE207 and 5 more
- 7A1N · Factor inhibiting hif-1 alpha in complex with ZN(II), 3-methyl-2- oxoglutarate, and… · ROQ A1008 · binds TYR145, LEU188, THR196, HIS199, ASP201, ASN205, PHE207, LYS214 and 5 more
- 7A1S · Factor inhibiting hif-1 alpha in complex with ZN(II), 3-methyl-2- oxoglutarate, and… · ROQ A609 · binds TYR145, LEU186, LEU188, THR196, HIS199, ASP201, ASN205, PHE207 and 5 more
Residues it binds most
ASN 6, HIS 6, LEU 6, ASP 6, ILE 6, LYS 6, PHE 6, THR 6, TRP 6, TYR 6 (residue and the binding sites it lines).
Found with
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