Ligand · RKZ

RKZ · 4-[2-methyl-3-[(2~{R})-2-phenoxypropyl]imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine

RKZ, 4-[2-methyl-3-[(2~{R})-2-phenoxypropyl]imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine (C21 H22 N6 O, 374.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component: RKZ
Formula: C21 H22 N6 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

RKZ in 2 structures; the first of them:

7AJY · Structure of DYRK1A in complex with compound 51 · RKZ A501 · binds ILE165, GLY166, LYS167, PHE170, VAL173, ALA186, LYS188, GLU203 and 12 more
7AJY · Structure of DYRK1A in complex with compound 51 · RKZ A501 · binds ILE165, LYS167, PHE170, ALA186, LYS188, GLU203, VAL222, PHE238 and 8 more

Residues it binds most

GLU 4, PHE 4, VAL 4, LEU 4, LYS 4, ALA 4, ASN 4, ASP 4, SER 4, ILE 3 (residue and the binding sites it lines).

Found with

CL · Chloride ion

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