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Ligand · RKQ

RKQ · 4-[2-methyl-3-(2-phenoxyethyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine

RKQ, 4-[2-methyl-3-(2-phenoxyethyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine (C20 H20 N6 O, 360.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
RKQ
Formula
C20 H20 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

RKQ in 2 structures; the first of them:

  • 7AJW · Structure of DYRK1A in complex with compound 46 · RKQ A501 · binds ILE165, GLY166, LYS167, PHE170, VAL173, ALA186, LYS188, GLU203 and 12 more
  • 7AJW · Structure of DYRK1A in complex with compound 46 · RKQ A501 · binds ILE165, GLY166, LYS167, PHE170, VAL173, ALA186, LYS188, GLU203 and 12 more

Residues it binds most

GLU 2, PHE 2, VAL 2, LEU 2, LYS 2, ALA 2, ASN 2, ASP 2, GLY 2, ILE 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

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