GL1X · GenesisL1 explorer

Ligand · RJE

RJE · 2-(2-methoxyethoxy)-6-(methylamino)-9-(phenylmethyl)-7H-purin-8-one

RJE, 2-(2-methoxyethoxy)-6-(methylamino)-9-(phenylmethyl)-7H-purin-8-one (C16 H19 N5 O3, 329.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
RJE
Formula
C16 H19 N5 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

RJE in 2 structures; the first of them:

  • 5ANT · Potent and selective inhibitors of MTH1 probe its role in cancer cell survival · RJE A1157 · binds TYR7, THR8, LEU9, LEU11, LEU20, PHE27, ASN33, GLY34 and 13 more
  • 5ANT · Potent and selective inhibitors of MTH1 probe its role in cancer cell survival · RJE A1157 · binds TYR7, THR8, LEU9, LEU11, LEU20, PHE27, ASN33, GLY34 and 13 more

Residues it binds most

PHE 6, GLY 6, LEU 6, ASP 6, TRP 6, MET 6, ASN 6, THR 6, TYR 6, VAL 6 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.