GL1X · GenesisL1 explorer

Ligand · RIE

RIE · (3R,5R)-7-[1-(4-fluorophenyl)-4-(1-methylethyl)-3-{methyl[(1R)-1-phenylethyl]carbamoyl}-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid

RIE, (3R,5R)-7-[1-(4-fluorophenyl)-4-(1-methylethyl)-3-{methyl[(1R)-1-phenylethyl]carbamoyl}-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid (C29 H36 F N3 O5, 525.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
RIE
Formula
C29 H36 F N3 O5
Class
ligand
Structures
2
PDB entries
1

Binding sites

RIE in 2 structures; the first of them:

  • 2R4F · Substituted Pyrazoles as Hepatselective HMG-COA reductase inhibitors · RIE A876 · binds ARG590, MET657, SER661, VAL683, SER684, ASN686, CYS688, ASP690 and 17 more
  • 2R4F · Substituted pyrazoles as hepatselective hmg-CoA reductase inhibitors · RIE A876 · binds ARG590, MET657, SER661, VAL683, SER684, ASN686, CYS688, ASP690 and 17 more

Residues it binds most

SER 8, ALA 8, LEU 8, LYS 8, ARG 8, ASN 8, CYS 8, ASP 8, GLU 8, GLY 8 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.