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Ligand · RHH

RHH · 4-[2-methyl-3-(2-pyridin-2-yloxyethyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine

RHH, 4-[2-methyl-3-(2-pyridin-2-yloxyethyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine (C19 H19 N7 O, 361.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
RHH
Formula
C19 H19 N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

RHH in 2 structures; the first of them:

  • 7AK2 · Structure of DYRK1A in complex with compound 53 · RHH A501 · binds ILE165, GLY166, LYS167, PHE170, VAL173, ALA186, LYS188, GLU203 and 11 more
  • 7AK2 · Structure of DYRK1A in complex with compound 53 · RHH A501 · binds ILE165, LYS167, PHE170, ALA186, LYS188, GLU203, VAL222, PHE238 and 9 more

Residues it binds most

GLU 4, PHE 4, VAL 4, LEU 4, LYS 4, ALA 4, ASN 4, ASP 4, ILE 4, MET 4 (residue and the binding sites it lines).

Found with

  • PO4 · Phosphate ion
  • DMS · Dimethyl sulfoxide

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