Ligand · RH8

RH8 · ~{N}-[3-fluoranyl-4-(4-methylpiperazin-1-yl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine

RH8, ~{N}-[3-fluoranyl-4-(4-methylpiperazin-1-yl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine (C21 H21 F N8, 404.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component: RH8
Formula: C21 H21 F N8
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

RH8 in 2 structures; the first of them:

7AK3 · CLK1 bound with CAF052 · RH8 A501 · binds LEU167, GLY168, GLU169, PHE172, VAL175, ALA189, LYS191, GLU206 and 12 more
7AK3 · CLK1 bound with CAF052 · RH8 A501 · binds LEU167, GLY168, VAL175, ALA189, LYS191, PHE241, GLU242, LEU243 and 6 more

Residues it binds most

LEU 2, VAL 2, GLU 2, GLY 2, ASP 2, PHE 2, ALA 2, LYS 2, ASN 1 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.