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Ligand · RFN

RFN · (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-(2-oxo-4-phenylpyridin-1(2H)-yl)butanamide

RFN, (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-(2-oxo-4-phenylpyridin-1(2H)-yl)butanamide (C17 H20 N2 O5 S, 364.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
RFN
Formula
C17 H20 N2 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

RFN in 2 structures; the first of them:

  • 3UHM · UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase in complex with inhibitor · RFN A303 · binds LEU18, HIS19, MET62, SER63, GLU77, HIS78, THR190, PHE191 and 12 more
  • 3UHM · Udp-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase in complex with inhibitor · RFN A303 · binds LEU18, HIS19, MET62, SER63, GLU77, HIS78, THR190, PHE191 and 12 more

Residues it binds most

HIS 2, ALA 2, GLY 2, LEU 2, SER 2, ASP 2, GLU 2, ILE 2, LYS 2, MET 2 (residue and the binding sites it lines).

Found with

  • GAI · Guanidine
  • ZN · Zinc ion
  • EDO · 1,2-ethanediol

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