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Ligand · RFE

RFE · L-Methionine Tenofovir

RFE, L-Methionine Tenofovir (C14 H23 N6 O5 P S, 418.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
RFE
Formula
C14 H23 N6 O5 P S
Class
ligand
Structures
4
PDB entries
2

Binding sites

RFE in 4 structures; the first of them:

  • 7AII · HIV-1 reverse transcriptase complex with DNA and L-methionine tenofovir with bound… · RFE A603 · binds LYS65, LYS66, ARG72, LEU74, ASP110, VAL111, GLY112, ASP113 and 8 more
  • 7AIJ · HIV-1 reverse transcriptase complex with DNA and L-methionine tenofovir · RFE C601 · binds LYS65, ARG72, LEU74, VAL111, GLY112, ASP113, ALA114, TYR115 and 7 more
  • 7AII · HIV-1 reverse transcriptase complex with DNA and L-methionine tenofovir with bound… · RFE A603 · binds LYS65, LYS66, ARG72, LEU74, ASP110, VAL111, ASP113, ALA114 and 6 more
  • 7AIJ · HIV-1 reverse transcriptase complex with DNA and L-methionine tenofovir · RFE C601 · binds LYS65, ARG72, ASP113, ALA114, TYR115, GLN151, ASP185, DT705 and 2 more

Residues it binds most

ASP 6, LYS 6, ALA 6, ARG 6, DC 6, DDG 6, DT 6, GLN 6, TYR 6, LEU 5 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion

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