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Ligand · RF7

RF7 · {(2R)-4-[hydroxy(methyl)amino]-4-oxo-2-phenylbutyl}phosphonic acid

RF7, {(2R)-4-[hydroxy(methyl)amino]-4-oxo-2-phenylbutyl}phosphonic acid (C11 H16 N O5 P, 273.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
RF7
Formula
C11 H16 N O5 P
Class
ligand
Structures
2
PDB entries
1

Binding sites

RF7 in 2 structures; the first of them:

  • 4Y6R · Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin… · RF7 A501 · binds LYS205, ASP231, SER232, GLU233, CYS268, SER269, SER270, GLY271 and 12 more
  • 4Y6R · Structure of plasmodium falciparum dxr in complex with a beta- substituted fosmidomycin… · RF7 A501 · binds LYS205, ASP231, SER232, GLU233, CYS268, SER269, SER270, GLY271 and 12 more

Residues it binds most

SER 4, LYS 4, GLU 4, GLY 4, MET 4, ASN 4, ASP 4, CYS 4, ILE 4, PRO 4 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • CL · Chloride ion
  • SO4 · Sulfate ion

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