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Ligand · RF6

RF6 · 4,6-diethylpyrimidin-2-amine

RF6, 4,6-diethylpyrimidin-2-amine (C8 H13 N3, 151.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
RF6
Formula
C8 H13 N3
Class
ligand
Structures
2
PDB entries
2

Binding sites

RF6 in 2 structures; the first of them:

  • 8BR9 · Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22 · RF6 B2101 · binds CYS1231, LEU1234, GLN1235, CYS1238
  • 8C3N · Stapled peptide SP30 in complex with humanised RadA mutant HumRadA22 · RF6 B2301 · binds GLN213, TYR216, GLN217, CYS2055, CYS1234, VAL1238

Residues it binds most

CYS 2, GLN 2, LEU 1, TYR 1, VAL 1 (residue and the binding sites it lines).

Found with

  • ADP · Adenosine-5'-diphosphate
  • MG · Magnesium ion

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