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Ligand · RCK

RCK · ~{N}-[(2-fluorophenyl)methyl]-6-(morpholin-4-ylmethylsulfanyl)-1-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-4-amine

RCK, ~{N}-[(2-fluorophenyl)methyl]-6-(morpholin-4-ylmethylsulfanyl)-1-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-4-amine (C25 H27 F N6 O S, 478.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding…

Component
RCK
Formula
C25 H27 F N6 O S
Class
ligand
Structures
1
PDB entries
1

Binding sites

RCK in 1 structure; the first of them:

  • 7AH3 · Kinase domain of csrc in complex with a pyrazolopyrimidine · RCK A601 · binds LEU273, VAL281, ALA293, LYS295, MET314, VAL323, ILE336, THR338 and 7 more

Residues it binds most

LEU 2, MET 2, VAL 2, ALA 2, ASP 2, GLU 2, GLY 2, ILE 2, LYS 2, SER 2 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol
  • GOL · Glycerol

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