GL1X · GenesisL1 explorer

Ligand · RBQ

RBQ · (8S)-2-(morpholin-4-yl)-9-[2-(propan-2-yloxy)ethyl]-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one

RBQ, (8S)-2-(morpholin-4-yl)-9-[2-(propan-2-yloxy)ethyl]-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one (C17 H25 F3 N4 O3, 390.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries).…

Component
RBQ
Formula
C17 H25 F3 N4 O3
Class
ligand
Structures
2
PDB entries
2

Binding sites

RBQ in 2 structures; the first of them:

  • 4UWG · Discovery of (2S)-8-((3R)-3-Methylmorpholin-4-yl)-1-(3-methyl-2-oxo… · RBQ A1873 · binds PHE612, SER614, PRO618, ILE634, LYS636, ASP644, TYR670, MET682 and 9 more
  • 5ANL · Crystal structure of VPS34 in complex with (2S)-8-((3R)-3… · RBQ A1870 · binds PHE612, SER614, PRO618, ILE634, LYS636, ASP644, TYR670, MET682 and 9 more

Residues it binds most

ILE 2, PHE 2, ASP 2, PRO 2, SER 2, GLN 2, LEU 2, LYS 2, MET 2, TYR 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.