RB6 · (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid

Binding sites

RB6 in 4 structures; the first of them:

• 5TX9 · Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R)… · RB6 A403 · binds ALA74, SER75, LEU115, SER139, GLY181, ALA182, ARG186, THR260 and 7 more
• 5TXI · Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex… · RB6 A401 · binds ALA74, SER75, LEU115, SER139, GLY181, ALA182, GLU183, ARG186 and 8 more
• 6G88 · Crystal structure of Enterococcus Faecium D63r Penicillin-Binding protein 5 (PBP5fm) · RB6 A700 · binds GLY421, SER422, LYS425, THR463, VAL465, SER466, TYR479, SER480 and 10 more
• 7RCY · Crystal structure of C. difficile penicillin-binding protein 2 in complex with… · RB6 A1001 · binds GLN489, GLY491, SER492, LYS495, TYR529, SER550, ASN552, ILE706 and 12 more

Residues it binds most

SER 8, THR 8, GLY 8, TYR 8, ALA 8, GLU 8, LYS 4, ASP 5, GLN 4, ARG 4 (residue and the binding sites it lines).

Found with

• ZN · Zinc ion
• NA · Sodium ion
• SO4 · Sulfate ion
• CL · Chloride ion
• GOL · Glycerol