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Ligand · RAB

RAB · 2-(6-amino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

RAB, 2-(6-amino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol (C10 H13 N5 O4, 267.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues…

Component
RAB
Formula
C10 H13 N5 O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

RAB in 4 structures; the first of them:

  • 1PW7 · Crystal Structure of E. coli purine nucleoside phosphorylase complexed with… · RAB A645 · binds MET64, ARG87, SER90, CYS91, GLY92, PHE159, VAL178, GLU179 and 5 more
  • 3GLQ · Crystal structure of S-adenosyl-L-homocysteine hydrolase from Burkholderia pseudomallei… · RAB A602 · binds LEU61, HIS62, THR64, GLN66, THR67, ASP139, GLU199, THR200 and 10 more
  • 1PW7 · Crystal structure of E. COLI purine nucleoside phosphorylase complexed with… · RAB A645 · binds MET64, ARG87, SER90, CYS91, GLY92, PHE159, VAL178, GLU179 and 5 more
  • 3GLQ · Crystal structure of S-adenosyl-L-homocysteine hydrolase from burkholderia pseudomallei… · RAB A602 · binds LEU61, HIS62, THR64, GLN66, THR67, ASP139, GLU199, THR200 and 10 more

Residues it binds most

GLU 10, MET 10, THR 4, ASP 10, HIS 4, LEU 4, SER 6, GLY 10, PHE 10, ARG 6 (residue and the binding sites it lines).

Found with

  • NAD · Nicotinamide-adenine-dinucleotide
  • PO4 · Phosphate ion

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