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Ligand · RA8

RA8 · N-(benzylsulfonyl)-L-leucyl-N-(4-{[amino(imino)methyl]amino}butyl)-L-prolinamide

RA8, N-(benzylsulfonyl)-L-leucyl-N-(4-{[amino(imino)methyl]amino}butyl)-L-prolinamide (C23 H38 N6 O4 S, 494.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
RA8
Formula
C23 H38 N6 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

RA8 in 2 structures; the first of them:

  • 1YPL · X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue RA-1008 · RA8 H5555 · binds HIS57, TYR60A, TRP60D, GLU97A, ASN98, LEU99, ILE174, ASP189 and 11 more
  • 1YPL · X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue ra-1008 · RA8 H5555 · binds HIS57, TYR60A, TRP60D, GLU97A, ASN98, LEU99, ILE174, ASP189 and 11 more

Residues it binds most

GLY 2, CYS 2, GLU 2, SER 2, TRP 2, ALA 2, ASN 2, ASP 2, HIS 2, ILE 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • GOL · Glycerol

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